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Patients need new approaches to treating sciatica pain.

Clinicians seek new interventions for treating sciatica pain.

We’re working to redefine interventional pain treatment for sciatica.


At Sollis, we’re developing an investigational therapy to treat patients for whom conservative sciatica pain treatments have been ineffective.

Our Phase 3 SERENITY-CM study will be initiating in 2023

Developing a new approach to treating sciatica pain

Our Clonidine Micropellet (clonidine hydrochloride extended-release epidural micropellet) investigational treatment is designed to target the source of sciatica pain over time, while also reducing inflammation at the injured nerve.* Our goal is to develop rapid, durable pain relief that allows healing—using a non-opioid, non-steroid medication.

Explore Sollis Clinical Trials

Study Summaries & Clinical Evidence

Learn more about clinical trials and review results and publications.

Learn more

Upcoming Trials

We are currently in the planning stages for upcoming trials. Check back soon for up-to-date information.

* The Sollis Clonidine Micropellet therapy is an investigational treatment for sciatica and has not been approved for use by the FDA.

  • Our Science
    • Micropellet Technology
    • Clonidine Therapy
  • Our Focus
    • Sciatica
    • Clinical trials
  • About Us
    • Overview
    • Leadership
    • Careers

CONTACT
P.O. Box 450
Hilliard, OH 43026
Phone. 614-636-4971
Email. [email protected]

© 2022 Sollis Therapeutics Inc.
Sollis Therapeutics is a registered trademark of Sollis Therapeutics, Inc.

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